作者: Arturo Casadevall , Ekaterina Dadachova , Liise-anne Pirofski
DOI: 10.1038/NRMICRO974
关键词: Passive antibody therapy 、 Immunization 、 Antimicrobial 、 Biology 、 Antibody 、 The Renaissance 、 Biological warfare 、 Immunology 、 Immunity 、 General Immunology and Microbiology
摘要: Antibody-based therapies are currently undergoing a renaissance. After being developed and then largely abandoned in the twentieth century, many antibody preparations now clinical use. However, most of reagents that available target non-infectious diseases. Interest using antibodies to treat infectious diseases is fuelled by wide dissemination drug-resistant microorganisms, emergence new relative inefficacy antimicrobial drugs immunocompromised hosts fact antibody-based only means provide immediate immunity against biological weapons. Given need for recent technological advances field immunoglobulin research, there considerable optimism regarding renewed applications therapy prevention treatment