Burn and trauma units as sources of methicillin-resistant Staphylococcus aureus.

摘要: At the time that methicillin-resistant Staphylococcus aureus (MRSA) began to achieve clinical prominence, it was thought be spread by exogenous vectors. Institution of rigorous infection control efforts, including isolation procedures, found have little effect on die frequency MRSA colonization burn wounds. It later handwashing sufficient prevent cross-contamination. Subsequently, has been shown patients can harboring at admission unit and multiple antimicrobial resistance develop among organisms reside in patient through plasmid-mediated transfer genes. Excessive use such agents as synthetic penicillins second- third-generation cephalosporins selected for survival these organisms. Currently, only available agent systemic treatment is vancomycin, which expensive associated with significant toxicity. Muciprocin a topical promises useful infections. Other are needed, since single drug combat infections seems likely encourage emergence resistant