Der Nachweis von Endomysium-und Transglutaminase-Antikörpern in der Diagnostik der Zöliakie

作者: Verena Oberhammer

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摘要: Vergleich von Endomysium- und Transglutaminase-Antikorpern bei verschiedenen Patientengruppen. Verglichen wurden EmA-IgA- TG-IgA-Antikorper-Test, wobei fur den Nachweis TG-IgA-Antikorper drei Testkits Anbietern verwendet wurden. Des weiteren EmA-IgG- TG-IgG-Antikorpertests durchgefuhrt die Ergebnissse miteinander verglichen. Endomysium- TG-IgA-Antikorper-Tests zeigten vergleichbar hohe Werte Spezifitat Sensitivitat, so dass der aufwendigere Endomysium-Antikorper-Test in Routinediagnostik durch Transglutaminase-Test ersetzt werden kann. Der EmA- TG-IgG-Antikorper ist v.a. haufig mit Zoliakie assoziertem Verdacht auf IgA-Mangel durchzufuhren.

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