Cerebral perfusion during low-flow cardiopulmonary bypass with circulatory arrest in rabbits — An experimental study for CPB in neonates

摘要: Cardiopulmonary bypass may be associated with multiorgan damage, resulting in either immediate or long-term effects (1, 2, 5). This damage occasionally related to inadequate regional tissue oxygen delivery. Several clinical and experimental studies have clearly shown the precise close correlation among electrical cerebral activity (EEG), blood flow (CBF), intracranial pressure (ICP), metabolic (CMRO2). The purpose of our study is assess perfusion neonates by evaluating differences CBF CMRO2-metabolism during low-flow CPB circulatory arrest deep hypothermic temperatures an model for heart- heart-lung-transplantation rabbits.