Age-related changes of methionine-enkephalin and beta-endorphin/beta-lipotropin immunoreactivity in human CSF.

作者: L. Alessio , S. Govoni , G. Salar , F. Battaini , R. Iavicoli

DOI: 10.1016/0024-3205(88)90403-1

关键词: Methionine enkephalinPeptide hormoneEndocrinologybeta-EndorphinAge relatedBeta-LipotropinChemistryInternal medicineCerebrospinal fluidSenescenceNeuropeptide

摘要: Methionine-enkephalin (ME-IR) and beta-endorphin (BE-IR) immunoreactive material CSF concentrations have been measured in subjects of different ages affected by lumbar or cervical disk hernia. The two peptides exhibited age-related trends. ME-IR levels rose significantly with age while no changes were observed the case BE-IR.

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