Genotoxic Potential of the Insecticide Imidacloprid in a Non-Target Organism (Oreochromis niloticus-Pisces)

作者: Yadira Ansoar-Rodríguez , Cintya A. Christofoletti , Ana Claudia Marcato , Jorge Evangelista Correia , Odair Correa Bueno

DOI: 10.4236/JEP.2015.612118

关键词: OreochromisMicronucleus testGenetic modelPesticideNile tilapiaImidaclopridGenotoxicityToxicologyComet assayBiology

摘要: The indiscriminate use of pesticides has become a serious environmental concern. Insecticide imidacloprid (IMI) is the second most widely used worldwide. In 2010, 1.934 tons IMI were sold in Brazil, mostly to be sugarcane crops. Several studies have detected its presence aquatic environment constituting risk non-target organisms. animals are organisms for biomonitoring They considered excellent genetic models detect mutagens. Among animal species, fish Oreochromis niloticus, commonly known as Nile tilapia, been evaluate DNA damage. present study therefore evaluated effect on material niloticus (Pisces) erythrocytes exposed different concentration (250; 125 and 62.5 μg/L) growing sugarcane. was measured using comet assay micronucleus (MN) test, assays that genotoxic results demonstrated concentrations tested induced primary damage DNA. also proved occurrence MN nuclear abnormalities at higher micronuclei other test. insecticide all chromosomal level highest tested. this show potential organism.

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