Is there an association between labor induction and attention-deficit/hyperactivity disorder among children?

摘要: There is evidence of destructive effects oxytocin use during labor on neurodevelopment. This meta-analysis pooled all observational studies to determine the association between induction and risk attention-deficit/hyperactivity disorder (ADHD) among children. All (case-control cohort) were reviewed until September 2020 after searches PubMed, Scopus, Web Science databases, gray literature, conference proceedings. The odds ratios (OR), relative (RR), 95% confidence intervals (CI (were calculated as random effect estimates studies. reviewed, including four cohort 2,885,743 participants three case-control 51,135 (10,961 with ADHD 40,174 in control groups) a sample size 2,936,878 participants. OR RR did not indicate significant children (OR, 1.13; CI, 0.90-1.35) (RR, 1.10; 0.96-1.24). findings showed that associated an increased However, more are needed investigate relationship ADHD.