作者: Steve Elliott , Elizabeth Pham , Iain C. Macdougall
DOI: 10.1016/J.EXPHEM.2008.08.003
关键词: Epoetin alfa 、 Mechanism of action 、 Pharmacology 、 Erythropoietin 、 Erythropoiesis 、 Medicine 、 Anemia 、 Darbepoetin alfa 、 Red blood cell 、 PEGylation
摘要: … mechanism but more prolonged action. Darbepoetin alfa is a hyperglycosylated EPO analog with an extended terminal half-life and a greater relative potency compared with rhEPO at …