作者: Matthew L. Clark , Courtney A. Tobin , Angela Sutton , Tricia Ann Missall
DOI: 10.1155/2018/5175319
关键词: Etiology 、 Granuloma annulare 、 Interleukin 17 、 Malignancy 、 Secukinumab 、 Dyslipidemia 、 Histiocyte 、 Thyroid disease 、 Dermatology 、 Medicine
摘要: Granuloma annulare (GA) is a common benign inflammatory skin condition classically presenting as skin-colored to erythematous dermal papules and annular plaques. Histologically, GA displays granulomatous infiltrate with palisaded histiocytes surrounding focally altered collagen. The exactly etiology of remains unknown, but it has been associated trauma, various infections, diabetes mellitus, malignancy, thyroid disease, dyslipidemia, several medications. In 2017, case developing in patient treated the interleukin 17A antagonist secukinumab was reported. Here we report second association use.