Granuloma Annulare in the Setting of Secukinumab

作者: Matthew L. Clark , Courtney A. Tobin , Angela Sutton , Tricia Ann Missall

DOI: 10.1155/2018/5175319

关键词: EtiologyGranuloma annulareInterleukin 17MalignancySecukinumabDyslipidemiaHistiocyteThyroid diseaseDermatologyMedicine

摘要: Granuloma annulare (GA) is a common benign inflammatory skin condition classically presenting as skin-colored to erythematous dermal papules and annular plaques. Histologically, GA displays granulomatous infiltrate with palisaded histiocytes surrounding focally altered collagen. The exactly etiology of remains unknown, but it has been associated trauma, various infections, diabetes mellitus, malignancy, thyroid disease, dyslipidemia, several medications. In 2017, case developing in patient treated the interleukin 17A antagonist secukinumab was reported. Here we report second association use.

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