The switch process in manic-depressive illness. Circadian variation in time of switch and sleep and manic ratings before and after switch.
作者： N. Sitaram , J. C. Gillin , W. E. Bunney
DOI: 10.1111/J.1600-0447.1978.TB06938.X
关键词: Morning 、 Sleep (system call) 、 Manic-depressive illness 、 Sleep time 、 Mania 、 Psychology 、 Psychiatry 、 Evening 、 Pediatrics 、 Circadian rhythm 、 Research data
摘要: Research data collected on 75 Bipolar I patients, hospitalized at the NIMH between 1963 and 1975, were reviewed to identify "switches" into out of mania. There 27 "slow" switches (i.e. occurring over a period 2--6 days) in 14 patients 89 "rapid" 24 hours or less) 35 patients. No patient showed both during his hospitalization. Among rapid switches, 52 mania 37 Rapid occurred significantly more often morning (7 a.m. 3 p.m.) than night (11 p.m. 7 a.m.) evening (3 11 p.m.). Estimated average sleep time prior switch significant drop as compared second, third fourth nights switch. Patients who switched rated manic 4 days following evening. sleeping less morning.
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