Using scanning contactless conductivity to optimise photografting procedures and capacity in the production of polymer ion-exchange monoliths

摘要: Capacitively coupled contactless conductivity detection (C4D) is utilised as a simple, rapid and non-invasive technique for the quantitative evaluation of ion-exchange capacity charged polymer monoliths in capillary format. A monomer, 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) was photografted onto 100 µm i.d. butyl methacrylate-co-ethylenedimethacrylate monolith number discrete 10 mm zones. By varying energy dose (J/cm2) during grafting each zone, density thus could be precisely controlled. Ion-exchange correlated with by measuring conductive response grafted region using scanning C4D techniques. Repeatability method excellent % RSD values 0.7% 2.4% obtained three replicate scans ungrafted regions single monolith, respectively. photografting process on separate also examined comparison profiles. The spatial accuracy probed which measure at measurement intervals low 1 along its entire length. Scanning used real time visualisation equilibration zones to permit optimisation washing procedures. Finally, applied methacrylate-co-AMPS-co-ethylenedimethacrylate copolymers direct correlation between concentration monomer polymerisation mixture. longitudinal homogeneity charge 0.3% RSD, demonstrating that functional evenly dispersed throughout bulk monolith. cross validated chromatographically breakthrough studies found closely correlate within 1% measurements made C4D.