Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein.
作者： Cynthia Brimer , James T. Dalton , Zixin Zhu , John Schuetz , Kazuto Yasuda
关键词: Transfection 、 Cytochrome P450 、 Biochemistry 、 P-glycoprotein 、 Molecular biology 、 CYP3A4 、 ATP-binding cassette transporter 、 Cytochrome P450 reductase 、 Cytochrome P-450 CYP3A 、 Biology 、 Enzyme
摘要: Purpose. To develop model polarized cell systems expressingcytochrome P4503A4, NADPH P450 reductase, and P-glycoprotein (Pgp).
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