On the nature of thumbs

作者: Günter P Wagner , Alexander O Vargas

DOI: 10.1186/GB-2008-9-3-213

关键词: Hox geneFunctional genomicsNumerical digitGeneticsBiological evolutionRegulation of gene expressionTetrapod (structure)BiologyEvolutionary biology

摘要: Asymmetric regulation of Hox gene expression pre-dates the appearance tetrapod digits, and was co-opted in development 'thumbness'. This asymmetric correlates with independent morphological evolutionary variation digit 1.

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