Chronotherapy tablet and methods related thereto

摘要: A chronotherapy tablet is provided for oral administration and the amelioration of at least one chronobiological condition within 24 hours comprising a substantially oblong core having longitudinal axis, first end second end, being comprised two superposed layers different compositions wherein an interface between each layer perpendicular to axis pharmacological composition; coating which envelops core, except exposed release face core. Methods are prevention and/or treatment asthma, arthritis (including, but not limited to, osteoarthritis rheumatoid arthritis), gastrointestinal disorders, cardiovascular disease hypertension, angina, myocardial infarction, stroke), cancer.