Remote dose-dependent effects of dry needling at distant myofascial trigger spots of rabbit skeletal muscles on reduction of substance P levels of proximal muscle and spinal cords.

作者: Yueh-Ling Hsieh , Chen-Chia Yang , Szu-Yu Liu , Li-Wei Chou , Chang-Zern Hong

DOI: 10.1155/2014/982121

关键词: Spinal cordDry needlingSurgeryIn patientBicepsSpinal Cord Dorsal HornAnatomySubstance PDose dependenceProximal MuscleMedicine

摘要: Background. Dry needling at distant myofascial trigger points is an effective pain management in patients with pain. However, the biochemical effects of remote dry are not well understood. This study evaluates different dosages on expressions substance P (SP) proximal muscle, spinal dorsal horns rabbits. Methods. Male New Zealand rabbits (2.5–3.0 kg) received spots a gastrocnemius (distant muscle) one (1D) or five sessions (5D). Bilateral biceps femoris (proximal muscles) and superficial laminaes L5-S2, T2-T5, C2-C5 were sampled immediately 5 days after to determine levels SP using immunohistochemistry western blot. Results. Immediately for 1D 5D, significantly decreased ipsilateral bilateral (). Five needling, these reduced immunoactivities found only animals receiving 5D Conclusions. effect involves reduction muscle laminaes, which may be closely associated control

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