The role of luteinizing hormone in folliculogenesis and ovulation induction.

摘要: Abstract Objective: To review the physiologic, pathophysiologic, and clinical roles of LH in follicle oocyte development maturation to assess effects content exogenous gonadotropin preparations used for ovulation induction. Design: Critical scientific literature devoted folliculogenesis. Evaluation comparison studies that different Conclusion(s): Folliculogenesis are complex processes require action both FSH. Luteinizing hormone is essential provide androgen substrate estrogen synthesis, which turn contributes may play a relevant role optimizing fertilization embryo quality. Although excessive secretion present some disorders detrimental reproductive function, this not applicable induction with hMG because menotropin does increase daily plasma levels. The results or FSH-only regimens did differ conducted patients polycystic ovary syndrome most ovulatory women undergoing assisted techniques; conversely, was clearly superior purified FSH treatment hypogonadotropic hypogonadism. Miscarriage rates were affected by use hMG. Thus, low but detectable concentrations positively influence outcome techniques.