Efficient Laboratory Methods to Assess Risk and Design Formulations
作者： Stephen R. Byrn , Roy J. Haskell
DOI: 10.1007/978-1-4939-1399-2_8
关键词: Section (archaeology) 、 Laboratory methods 、 Class (computer programming) 、 Biochemical engineering 、 Drug product 、 Computer science
摘要: This chapter provides an overview of this section and discusses various strategies to reduce risk design formulations. It a stepwise strategy outlines the involved in incorporating different solid forms drugs into drug products. addresses solubility, BCS class, instability, formulation design.
springer.com
sci-hub.st 参考文章(20)
M. Joan Taylor, Sangeeta Tanna, Tarsem Sahota, In Vivo Study of a Polymeric Glucose-Sensitive Insulin Delivery System Using a Rat Model Journal of Pharmaceutical Sciences. ,vol. 99, pp. 4215- 4227 ,(2010) , 10.1002/JPS.22138
Ann Newman, Gregory Knipp, George Zografi, Assessing the performance of amorphous solid dispersions. Journal of Pharmaceutical Sciences. ,vol. 101, pp. 1355- 1377 ,(2012) , 10.1002/JPS.23031
Roger Vandecruys, Jef Peeters, Geert Verreck, Marcus E. Brewster, Use of a screening method to determine excipients which optimize the extent and stability of supersaturated drug solutions and application of this system to solid formulation design. International Journal of Pharmaceutics. ,vol. 342, pp. 168- 175 ,(2007) , 10.1016/J.IJPHARM.2007.05.006
Qingyan Hu, Duk Soon Choi, Hitesh Chokshi, Navnit Shah, Harpreet Sandhu, Highly efficient miniaturized coprecipitation screening (MiCoS) for amorphous solid dispersion formulation development. International Journal of Pharmaceutics. ,vol. 450, pp. 53- 62 ,(2013) , 10.1016/J.IJPHARM.2013.04.040
John K. Haleblian, Characterization of Habits and Crystalline Modification of Solids and Their Pharmaceutical Applications Journal of Pharmaceutical Sciences. ,vol. 64, pp. 1269- 1288 ,(1975) , 10.1002/JPS.2600640805
Jochem Alsenz, Manfred Kansy, High throughput solubility measurement in drug discovery and development Advanced Drug Delivery Reviews. ,vol. 59, pp. 546- 567 ,(2007) , 10.1016/J.ADDR.2007.05.007
John D. Mullins, Thomas J. Macek, Some Pharmaceutical Properties of Novobiocin **Received August 21, 1959, from Merck Sharp and Dohme Research Laboratories, West Point, Pa. Journal of the American Pharmaceutical Association (Scientific ed.). ,vol. 49, pp. 245- 248 ,(1960) , 10.1002/JPS.3030490417
Eihei FUKUOKA, Midori MAKITA, Yasuo NAKAMURA, Glassy State of Pharmaceuticals. V. Relaxation during Cooling and Heating of Glass by Differential Scanning Calorimetry Chemical & Pharmaceutical Bulletin. ,vol. 39, pp. 2087- 2090 ,(1991) , 10.1248/CPB.39.2087
Grace A. Ilevbare, Lynne S. Taylor, Liquid–Liquid Phase Separation in Highly Supersaturated Aqueous Solutions of Poorly Water-Soluble Drugs: Implications for Solubility Enhancing Formulations Crystal Growth & Design. ,vol. 13, pp. 1497- 1509 ,(2013) , 10.1021/CG301679H
Stephen M. Berge, Lyle D. Bighley, Donald C. Monkhouse, Review ArticlePharmaceutical Salts Journal of Pharmaceutical Sciences. ,vol. 66, ,(1977) , 10.1002/JPS.2600660104