Meta-analysis of longitudinal cohort studies of suicide risk assessment among psychiatric patients: heterogeneity in results and lack of improvement over time

作者: Matthew Large , Muthusamy Kaneson , Nicholas Myles , Hannah Myles , Pramudie Gunaratne

DOI: 10.1371/JOURNAL.PONE.0156322

关键词: Meta-analysisCohort studySuicidal ideationPoison controlConfidence intervalPsychiatryPublication biasSuicide preventionRisk assessmentMedicine

摘要: OBJECTIVE: It is widely assumed that the clinical care of psychiatric patients can be guided by estimates suicide risk and using patient characteristics to define a group high-risk patients. However, statistical strength reliability categorization unknown. Our objective was investigate odds in compared lower-risk categories rates groups. METHOD: We located longitudinal cohort studies where or people who had made attempts were stratified into groups for with mortality as outcome searching peer reviewed publications indexed PubMed PsychINFO. Electronic searches supplemented hand included relevant review articles. Two authors independently extracted data regarding effect size, study population design from 53 samples risk-assessed reported 37 studies. RESULTS: The pooled among calculated random effects meta-analysis 4.84 (95% Confidence Interval (CI) 3.79-6.20). Between-study heterogeneity very high (I2 = 93.3). There no evidence more recent greater than older Over an average follow up period 63 months proportion suicides 5.5% 0.9% meta-analytically derived sensitivity specificity 56% 79% respectively. publication bias favour inflated CONCLUSIONS: categorizations based on presence multiple factors does not greatly exceed association between individual suicide. A statistically strong reliable method usefully distinguish remains elusive. Language: en

参考文章(68)
M. Krupinski, A. Fischer, R. Grohmann, R.R. Engel, M. Hollweg, H.-J. Möller, Schizophrene Psychosen und Kliniksuizid Der Nervenarzt. ,vol. 71, pp. 906- 911 ,(2000) , 10.1007/S001150050682
Trine Madsen, Merete Nordentoft, Drs Madsen and Nordentoft Reply The Journal of Clinical Psychiatry. ,vol. 73, pp. 1034- 1035 ,(2012) , 10.4088/JCP.12LR07795A
Bo Runeson, Axel Haglund, Paul Lichtenstein, Dag Tidemalm, Suicide risk after nonfatal self-harm: a national cohort study, 2000-2008. The Journal of Clinical Psychiatry. ,vol. 77, pp. 240- 246 ,(2016) , 10.4088/JCP.14M09453
Development of a clinical instrument to estimate suicide risk. American Journal of Psychiatry. ,vol. 142, pp. 680- 686 ,(1985) , 10.1176/AJP.142.6.680
Chandra Oleksiewicz, Allison Low, Maya Elin O'Neil, Susan Carson, Kimberly Peterson, Elizabeth M Haney, Devan Kansagara, Lauren M Denneson, Suicide Risk Factors and Risk Assessment Tools: A Systematic Review Series:VA Evidence-based Synthesis Program Reports. ,(2012)
Carol Chu, Kelly M. Klein, Jennifer M. Buchman-Schmitt, Melanie A. Hom, Christopher R. Hagan, Thomas E. Joiner, Routinized Assessment of Suicide Risk in Clinical Practice: An Empirically Informed Update Journal of Clinical Psychology. ,vol. 71, pp. 1186- 1200 ,(2015) , 10.1002/JCLP.22210
John F. McCarthy, Robert M. Bossarte, Ira R. Katz, Caitlin Thompson, Janet Kemp, Claire M. Hannemann, Christopher Nielson, Michael Schoenbaum, Predictive Modeling and Concentration of the Risk of Suicide: Implications for Preventive Interventions in the US Department of Veterans Affairs American Journal of Public Health. ,vol. 105, pp. 1935- 1942 ,(2015) , 10.2105/AJPH.2015.302737
M. Large, G. Smith, S. Sharma, O. Nielssen, S. P. Singh, Systematic review and meta-analysis of the clinical factors associated with the suicide of psychiatric in-patients. Acta Psychiatrica Scandinavica. ,vol. 124, pp. 18- 29 ,(2011) , 10.1111/J.1600-0447.2010.01672.X
Katarina Skogman, Margot Als�n, Agneta �jehagen, Sex differences in risk factors for suicide after attempted suicide-a follow-up study of 1052 suicide attempters. Social Psychiatry and Psychiatric Epidemiology. ,vol. 39, pp. 113- 120 ,(2004) , 10.1007/S00127-004-0709-9
J. D. Ribeiro, J. C. Franklin, K. R. Fox, K. H. Bentley, E. M. Kleiman, B. P. Chang, M. K. Nock, Self-injurious thoughts and behaviors as risk factors for future suicide ideation, attempts, and death: a meta-analysis of longitudinal studies. Psychological Medicine. ,vol. 46, pp. 225- 236 ,(2016) , 10.1017/S0033291715001804