Drug-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis

作者: Peter O. Fritsch , Alexis Sidoroff

DOI: 10.2165/00128071-200001060-00003

关键词: DermatologyPharmacotherapyAllopurinolDrug-induced Stevens-Johnson syndromePopulationPharmacology toxicologyNonsteroidalMedicineToxic epidermal necrolysis

摘要: Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare (occurring in approximately 2 to 3 people/million population/year Europe and the US), life-threatening, intolerance reaction of skin. It most often caused by drugs (most commonly sulfonamides, nonsteroidal anti-inflammatory drugs, antimalarials, anticonvulsants, allopurinol).

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