An approach to evaluating the therapeutic misconception

摘要: rt natural worry among bioethicists is that persons ., j| with severe neurological or psychiatric disorders i may be so desperate for a cure they are par ticularly vulnerable to exploitation in high-risk research studies because under therapeutic misconcep tion. Although Appelbaum and colleagues first described the misconception over 25 years ago,1 concept remains unsettled, difficulties of deter mining if participants exhibit has become increasingly apparent. Some authors have questioned ubiquity ethical impor tance misconception2 others suggested classification phenomena related misconception,3 while still expanded categories concern.4 Two teams recently reported high prevalence misconception,5 but these acknowledge there "lack agreement conceptual literature; [researchers] not defined measured [the misconception] same way";6 been "used by various denote number related, always identical, concepts"; "there yet con sensus about how operationalize miscon ception."7 A recent workshop, apparently intended develop consensus definition, instead released "draft dimen sions" demonstrate continuing disagreements regarding it.8 The report proposes defi nition does refer anything "therapeutic." proposed definition says tion occurs when individuals fail understand