Protein Kinase C Dependent Inhibition of Kir3.2 (GIRK2) Channel Activity and Its Molecular Determinants
作者： Scott Adney
DOI: 10.25772/6457-0944
关键词: Protein kinase C 、 TRPC1 、 Biophysics 、 G protein-coupled inwardly-rectifying potassium channel 、 Channel (broadcasting) 、 Potassium channel 、 Chemistry
摘要: … diverse modulatory factors that couple to PIP2-dependent gating. Channels in the Kir3 (GIRK) … whereby phosphorylation of Ser-196 recruits a critical gating residue, Arg-201, away from …
sci-hub.st 参考文章(90)
Diomedes E. Logothetis, Yoshihisa Kurachi, Jonas Galper, Eva J. Neer, David E. Clapham, The βγ subunits of GTP-binding proteins activate the muscarinic K + channel in heart Nature. ,vol. 325, pp. 321- 326 ,(1987) , 10.1038/325321A0
Atsushi Inanobe, Yukiko Yoshimoto, Yoshiyuki Horio, Ken-Ichiro Morishige, Hiroshi Hibino, Shigeto Matsumoto, Yoshimitsu Tokunaga, Toshihiro Maeda, Yutaka Hata, Yoshimi Takai, Yoshihisa Kurachi, Characterization of G-Protein-Gated K+Channels Composed of Kir3.2 Subunits in Dopaminergic Neurons of the Substantia Nigra The Journal of Neuroscience. ,vol. 19, pp. 1006- 1017 ,(1999) , 10.1523/JNEUROSCI.19-03-01006.1999
Jong-Woo Sohn, Ajin Lim, Suk-Ho Lee, Won-Kyung Ho, Decrease in PIP2-channel interactions is the final common mechanism involved in PKC- and arachidonic acid-mediated inhibitions of GABAB -activated K+ current The Journal of Physiology. ,vol. 582, pp. 1037- 1046 ,(2007) , 10.1113/JPHYSIOL.2007.137265
Jong-Woo Sohn, Doyun Lee, Hana Cho, Wonil Lim, Hee-Sup Shin, Suk-Ho Lee, Won-Kyung Ho, Receptor‐specific inhibition of GABAB‐activated K+ currents by muscarinic and metabotropic glutamate receptors in immature rat hippocampus The Journal of Physiology. ,vol. 580, pp. 411- 422 ,(2007) , 10.1113/JPHYSIOL.2006.125914
Diomedes E. Logothetis, Dmitry Lupyan, Avia Rosenhouse-Dantsker, Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding The Journal of Physiology. ,vol. 582, pp. 953- 965 ,(2007) , 10.1113/JPHYSIOL.2007.133157
Hailin Zhang, Cheng He, Xixin Yan, Tooraj Mirshahi, Diomedes E. Logothetis, Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactions. Nature Cell Biology. ,vol. 1, pp. 183- 188 ,(1999) , 10.1038/11103
Maria Torrecilla, Cheryl L. Marker, Stephanie C. Cintora, Markus Stoffel, John T. Williams, Kevin Wickman, G-protein-gated potassium channels containing Kir3.2 and Kir3.3 subunits mediate the acute inhibitory effects of opioids on locus ceruleus neurons. The Journal of Neuroscience. ,vol. 22, pp. 4328- 4334 ,(2002) , 10.1523/JNEUROSCI.22-11-04328.2002
P. R. Stanfield, Yasuko Nakajima, Kazuhiko Yamaguchi, Substance P raises neuronal membrane excitability by reducing inward rectification Nature. ,vol. 315, pp. 498- 501 ,(1985) , 10.1038/315498A0
Saverio Gentile, Ion Channel Phosphorylopathy: a Link between Genomic Variation and Human Disease ChemMedChem. ,vol. 7, pp. 1757- 1761 ,(2012) , 10.1002/CMDC.201200236
Hai-Long An, Shou-Qin Lü, Jun-Wei Li, Xuan-Yu Meng, Yong Zhan, Meng Cui, Mian Long, Hai-Lin Zhang, Diomedes E. Logothetis, The Cytosolic GH Loop Regulates the Phosphatidylinositol 4,5-Bisphosphate-induced Gating Kinetics of Kir2 Channels Journal of Biological Chemistry. ,vol. 287, pp. 42278- 42287 ,(2012) , 10.1074/JBC.M112.418640