Something old, something borrowed: Admixture and adaptation in human evolution
作者： Michael Dannemann , Fernando Racimo
DOI: 10.1016/J.GDE.2018.05.009
关键词: Adaptation 、 Denisovan 、 Biology 、 Human evolution 、 Neanderthal 、 Ancient DNA 、 Human genetics 、 Archaic humans 、 Population 、 Evolutionary biology
摘要: The sequencing of ancient DNA from archaic humans-Neanderthals and Denisovans-has revealed that modern humans interbred at least twice during the Pleistocene. field human paleogenomics has now turned its attention towards understanding nature this genetic legacy in gene pool present-day humans. What exactly did obtain interbreeding with Neanderthals Denisovans? Was introgressed material beneficial, neutral or maladaptive? Can differences phenotypes among populations be explained by introgression? These questions are prime importance for our recent evolution, but will require careful computational modeling extensive functional assays before they can answered full. Here, we review literature characterizing likely biological consequences their carriers. We focus particularly on haplotypes were beneficial to as expanded across globe, ways understand how harboring these evolved over time.
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Qiaomei Fu, Mateja Hajdinjak, Oana Teodora Moldovan, Silviu Constantin, Swapan Mallick, Pontus Skoglund, Nick Patterson, Nadin Rohland, Iosif Lazaridis, Birgit Nickel, Bence Viola, Kay Prüfer, Matthias Meyer, Janet Kelso, David Reich, Svante Pääbo, None, An early modern human from Romania with a recent Neanderthal ancestor Nature. ,vol. 524, pp. 216- 219 ,(2015) , 10.1038/NATURE14558
Fernando Racimo, Sriram Sankararaman, Rasmus Nielsen, Emilia Huerta-Sánchez, Evidence for archaic adaptive introgression in humans Nature Reviews Genetics. ,vol. 16, pp. 359- 371 ,(2015) , 10.1038/NRG3936
Morten E. Allentoft, Martin Sikora, Karl-Göran Sjögren, Simon Rasmussen, Morten Rasmussen, Jesper Stenderup, Peter B. Damgaard, Hannes Schroeder, Torbjörn Ahlström, Lasse Vinner, Anna-Sapfo Malaspinas, Ashot Margaryan, Tom Higham, David Chivall, Niels Lynnerup, Lise Harvig, Justyna Baron, Philippe Della Casa, Paweł Dąbrowski, Paul R. Duffy, Alexander V. Ebel, Andrey Epimakhov, Karin Frei, Mirosław Furmanek, Tomasz Gralak, Andrey Gromov, Stanisław Gronkiewicz, Gisela Grupe, Tamás Hajdu, Radosław Jarysz, Valeri Khartanovich, Alexandr Khokhlov, Viktória Kiss, Jan Kolář, Aivar Kriiska, Irena Lasak, Cristina Longhi, George McGlynn, Algimantas Merkevicius, Inga Merkyte, Mait Metspalu, Ruzan Mkrtchyan, Vyacheslav Moiseyev, László Paja, György Pálfi, Dalia Pokutta, Łukasz Pospieszny, T. Douglas Price, Lehti Saag, Mikhail Sablin, Natalia Shishlina, Václav Smrčka, Vasilii I. Soenov, Vajk Szeverényi, Gusztáv Tóth, Synaru V. Trifanova, Liivi Varul, Magdolna Vicze, Levon Yepiskoposyan, Vladislav Zhitenev, Ludovic Orlando, Thomas Sicheritz-Pontén, Søren Brunak, Rasmus Nielsen, Kristian Kristiansen, Eske Willerslev, Population genomics of Bronze Age Eurasia Nature. ,vol. 522, pp. 167- 172 ,(2015) , 10.1038/NATURE14507
Julien Y. Dutheil, Kasper Munch, Kiwoong Nam, Thomas Mailund, Mikkel H. Schierup, Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low Divergence PLOS Genetics. ,vol. 11, pp. e1005451- ,(2015) , 10.1371/JOURNAL.PGEN.1005451
B. Vernot, J. M. Akey, Resurrecting Surviving Neandertal Lineages from Modern Human Genomes Science. ,vol. 343, pp. 1017- 1021 ,(2014) , 10.1126/SCIENCE.1245938
Qiaomei Fu, Heng Li, Priya Moorjani, Flora Jay, Sergey M. Slepchenko, Aleksei A. Bondarev, Philip L. F. Johnson, Ayinuer Aximu-Petri, Kay Prüfer, Cesare de Filippo, Matthias Meyer, Nicolas Zwyns, Domingo C. Salazar-García, Yaroslav V. Kuzmin, Susan G. Keates, Pavel A. Kosintsev, Dmitry I. Razhev, Michael P. Richards, Nikolai V. Peristov, Michael Lachmann, Katerina Douka, Thomas F. G. Higham, Montgomery Slatkin, Jean-Jacques Hublin, David Reich, Janet Kelso, T. Bence Viola, Svante Pääbo, Genome sequence of a 45,000-year-old modern human from western Siberia Nature. ,vol. 514, pp. 445- 449 ,(2014) , 10.1038/NATURE13810
Bernard Y. Kim, Kirk E. Lohmueller, Selection and Reduced Population Size Cannot Explain Higher Amounts of Neandertal Ancestry in East Asian than in European Human Populations American Journal of Human Genetics. ,vol. 96, pp. 454- 461 ,(2015) , 10.1016/J.AJHG.2014.12.029
Daven C. Presgraves, Sex chromosomes and speciation in Drosophila Trends in Genetics. ,vol. 24, pp. 336- 343 ,(2008) , 10.1016/J.TIG.2008.04.007
David Reich, Richard E. Green, Martin Kircher, Johannes Krause, Nick Patterson, Eric Y. Durand, Bence Viola, Adrian W. Briggs, Udo Stenzel, Philip L. F. Johnson, Tomislav Maricic, Jeffrey M. Good, Tomas Marques-Bonet, Can Alkan, Qiaomei Fu, Swapan Mallick, Heng Li, Matthias Meyer, Evan E. Eichler, Mark Stoneking, Michael Richards, Sahra Talamo, Michael V. Shunkov, Anatoli P. Derevianko, Jean-Jacques Hublin, Janet Kelso, Montgomery Slatkin, Svante Pääbo, Genetic history of an archaic hominin group from Denisova Cave in Siberia Nature. ,vol. 468, pp. 1053- 1060 ,(2010) , 10.1038/NATURE09710
Emilia Huerta-Sánchez, Xin Jin, Asan, Zhuoma Bianba, Benjamin M. Peter, Nicolas Vinckenbosch, Yu Liang, Xin Yi, Mingze He, Mehmet Somel, Peixiang Ni, Bo Wang, Xiaohua Ou, Huasang, Jiangbai Luosang, Zha Xi Ping Cuo, Kui Li, Guoyi Gao, Ye Yin, Wei Wang, Xiuqing Zhang, Xun Xu, Huanming Yang, Yingrui Li, Jian Wang, Jun Wang, Rasmus Nielsen, Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA Nature. ,vol. 512, pp. 194- 197 ,(2014) , 10.1038/NATURE13408