Late diagnosis of chronic renal failure and mortality on maintenance dialysis

作者: R. Sesso , A. G. Belasco

DOI: 10.1093/OXFORDJOURNALS.NDT.A027207

关键词: Hazard ratioSurgeryDiabetes mellitusSurvival rateComorbidityPeritoneal dialysisDialysisKidney diseaseInternal medicineProportional hazards modelMedicine

摘要: Background. Recent observations in our country have shown that late diagnosis of chronic renal failure (CRF) is an important cause referral and commencement maintenance dialysis. We prospectively investigated the influence CRF on patient mortality during dialysis therapy. Methods. Among 184 consecutive patients with nondiabetic end-stage disease starting at Federal University Hospital city Sao Paulo, 106 had a (less than 1 month before dialysis) 78 early diagnosis. During first 6 months treatment, survival was compared two groups, using Kaplan-Meier method Cox proportional hazards model. Results. Six-month rate lower group (69% versus 87%, / > <0.01). In group, hazard ratio 2.77 (95% CI, 1.36-5.66) times group. multivariate analysis, after adjusting for age, comorbid illness, serum biochemical measurements, time did not remain significantly associated risk. this pulmonary infection, low albumin were significant predictors mortality. Conclusions. Patients higher risk This increased related to conditions, some which could be prevented by predialysis care. Interventions promote adequate follow-up need evaluated if improve.

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