A 10 year follow-up of semi-annual screening for early detection of lung cancer in the Erfurt County, GDR

摘要: A prospective and controlled study for early detection of lung cancer in the county Erfurt with a follow-up 10 years is presented. collective 41,532 males born between 1907 1932 was screened by chest fluorography at 6 month intervals compared control group consisting 102,348 same age, who were about 18 months. No significant reduction overall mortality achieved. Semi-annual screening brought higher rate (9%/6.5%), an increase resection (28%/19%) 5 year survival rates (52%; 27%/39%; 19%) resected patients than intervals. Among those refused or surgically untreatable, difference two investigation groups lasted only up to 12 months barrier. This regarded as effect lead-time bias. Fluorographic effective peripheral cancers. Patients central cancers did not show differences rates. In both considered together surgical therapy possible mainly had been detected (resection rate: 48%; yr 26.9%). The all others amounted 9%, 1.4%. Therefore we consider time chance high risk spite absence mortality.