Pregnancy outcome in liver transplant recipients

摘要: Abstract Objective To evaluate pregnancy course, complications, and outcomes in liver transplant recipients. Methods We conducted a retrospective review of 38 pregnancies conceived between 1992 2002 29 women who underwent transplantation at Mount Sinai Medical Center. Results The most common primary disease was autoimmune hepatitis. All patients were on immunosuppressive regimens that included cyclosporine A or tacrolimus. There four spontaneous first-trimester abortions ten terminations for worsening function. interval from to shorter the group had (24.4 ± 24.3 months) as compared with live births (47.8 28.7 months), P = .02. 24 20 patients. mean gestational age delivery 36.4 weeks, birth weight 2762 g. Pregnancy complications preeclampsia (20.8%), chronic hypertension hemolysis, elevated enzymes, low platelets syndrome (8.3%), creatinine 1.3 mg/dL more (25.0%), anemia (33.3%), diabetes (37.5%), cesarean (45.8%), preterm less than 37 weeks (29.2%), intrauterine growth restriction (16.7%), biopsy-proven graft rejection during (16.7%). no neonatal deaths. 5-minute Apgar scores greater 7. Four minor congenital anomalies noted. Before 1997, there five maternal deaths, 10–54 months after pregnancy. our population those delivered 1997 1998 2002. Conclusion planned least 2 years stable allograft function can have excellent outcome.