Technologies for systematic analysis of eukaryotic transcriptomes

作者: Robert L. Strausberg

DOI: 10.1002/047001153X.G207107

关键词: Emerging technologiesGenomeTranscriptomeGene expressionGeneticsComplementary DNADNA sequencingBiologyMicroarrayGeneComputational biology

摘要: Comprehensive high-throughput analysis of the eukaryotic transcriptome provides unprecedented opportunity to understand gene structure and expression, use that knowledge gain perspective biological function. During past decade, several new technologies based on DNA sequencing hybridization approaches have been developed applied analysis. In this overview, applications these current are discussed, as is need for continued technology development. Keywords: gene expression; cDNA; SAGE; MPSS; microarray; genome

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