Metabolic Syndrome and Subclinical Hypothyroidism: A Type 2 Diabetes-Dependent Association.

摘要: Introduction. Subclinical hypothyroidism (ScH) is an endocrine alteration that related to cardiovascular risk factors, including those categorized as components of the Metabolic Syndrome (MS). However, findings in prior reports regarding association between these alterations are inconsistent. The purpose this study was determine relationship both entities adult subjects from Maracaibo City, Venezuela. Materials and Methods. City Prevalence Study a descriptive, cross-sectional with random multistage sampling. In substudy, 391 individuals genders were selected TSH, free T3, T4 tests performed well complete lipid profile, fasting glycaemia, insulin blood values. ScH defined according National Health Nutrition Examination Survey (NHANES) criteria: high TSH (≥4.12mUI/L) normal (0.9-1,9 ng/dL) without personal history thyroid disease. MS IDF/AHA/NHLBI/WHF/IAS/IASO-2009 criteria. A multiple logistic regression analysis used assess diagnosis. Results. Of evaluated population, 10.5% (n=41) diagnosed ScH, higher prevalence women (female: 13.6% versus male: 7.7%; χ2=3.56, p=0.05). Likewise, 56.1% (n=23) (χ2=4.85; p=0.03), being hyperglycemia main associated criterion (χ2=11.7; p=0.001). multivariable analysis, it observed exclusive presence type 2 diabetes mellitus (T2DM) OR: 3.22 (1.14-9.14); p=0.03. Conclusion. our population dependent on hyperglycemia, specifically T2DM diagnosis, vary previously reported Latin American subjects.