Defective ribosomal products (DRiPs): a major source of antigenic peptides for MHC class I molecules?

作者: J W Yewdell , L C Antón , J R Bennink

DOI:

关键词: Protein biosynthesisRibosomal RNAProteasesBiochemistryPeptide BiosynthesisBiologyAntigen presentationMHC class IIntracellular parasiteTranslation (biology)

摘要: … Little is known about the nature of the polypeptides that serve as substrates for peptidogenic cytosolic proteases. We propose that a significant source of self and viral peptides are …

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