Antimicrobial silver grafts for prevention and treatment of vascular graft infection

摘要: In vascular surgery, graft infection remains a serious limb-threatening and often life-threatening complication, despite progress in the last several decades. During past 3 decades, prevention of surgical site predominantly relied on availability effective perioperative antibiotic prophylaxis or use systemic antibiotics for treatment infections after their clinical manifestation. However, evidence prophylactic effect exists only patients with vein grafts, who are at lower risk compared to receiving prosthetic material. Furthermore, because changed epidemiology bacterial susceptibility against today, reliance efficacy must be done caution. The outlook current trends indicates that maximum effort is needed maintain balance. Simply looking new will not lead an additional decrease rate surgery. Because consequences surgery increasing resistance causative micro-organisms, future strategy deal needs shift from manifest strong focus primary infection, particularly procedures involving materials. This article summarizes strategies reviews literature antimicrobial grafts using antiseptic agents instead achieve efficacy. Specific emphasis put silver its infection.