Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis
作者： Mortimer Korf-Klingebiel , Kai C Wollert , Simon J Conway , Gergana Dobreva , Manuel Mayr
DOI: 10.1007/S00395-021-00862-Y
关键词: Downregulation and upregulation 、 Fibroblast 、 Pressure overload 、 Angiogenesis 、 GATA6 、 Heart failure 、 GATA4 、 Cell biology 、 Medicine 、 Transcription factor
摘要: … -4 or GATA-6 in fibroblasts had no effect, while their compound deletion reduced the myocardial angiogenic … lacking either Gata4, Gata6 or both, revealed upregulation of several anti-…
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