Selective immunosuppression in mice of natural killer cell activity by ochratoxin A.

作者: Dori R. Germolec , Michael F. Ackermann , Michael I. Luster , Charles W. Jameson , Howard T. Hayes

DOI:

关键词: ImmunologyPharmacologyBiologyCarcinogenNatural killer cellOchratoxinCarcinogenesisOchratoxin ACellular immunityImmune systemInterferon

摘要: … interferon levels were responsible for suppression of NK activity. Although endoge nous interferon … -induced serum interferon levels were markedly reduced in ochratoxin A treated mice, …

参考文章(19)
M.G. Prior, C.S. Sisodia, The effects of ochratoxin A on the immune response of Swiss mice. Canadian journal of comparative medicine. ,vol. 46, pp. 91- 96 ,(1982)
D Taramelli, H T Holden, L Varesio, Mechanism of lymphocyte activation. II. Requirements for macromolecular synthesis in the production of lymphokines. Journal of Immunology. ,vol. 125, pp. 2810- 2817 ,(1980)
Hans Olof Sj�ren, Transplantation Methods as a Tool for Detection of Tumor-specific Antigens* Progress in Experimental Tumor Research. ,vol. 6, pp. 289- 322 ,(1965) , 10.1159/000391374
C W Reynolds, R B Herberman, In vitro augmentation of rat natural killer (NK) cell activity. Journal of Immunology. ,vol. 126, pp. 1581- 1585 ,(1981)
Inhibition of the Activity of Mouse Natural Killer Cells by Urethan Journal of the National Cancer Institute. ,vol. 66, pp. 543- 548 ,(1981) , 10.1093/JNCI/66.3.543
E E Creppy, F C Størmer, R Röschenthaler, G Dirheimer, Effects of two metabolites of ochratoxin A, (4R)-4-hydroxyochratoxin A and ochratoxin alpha, on immune response in mice. Infection and Immunity. ,vol. 39, pp. 1015- 1018 ,(1983) , 10.1128/IAI.39.3.1015-1018.1983
P. Krogh, Benedicte Hald, E. Jonas Pedersen, OCCURRENCE OF OCHRATOXIN A AND CITRININ IN CEREALS ASSOCIATED WITH MYCOTOXIC PORCINE NEPHROPATHY Acta Pathologica Microbiologica Scandinavica Section B Microbiology and Immunology. ,vol. 81, pp. 689- 695 ,(2009) , 10.1111/J.1699-0463.1973.TB02261.X
G.G.B Klaus, Catherine M Hawrylowicz, Cell-cycle control in lymphocyte stimulation. Immunology Today. ,vol. 5, pp. 15- 19 ,(1984) , 10.1016/0167-5699(84)90060-4
M.J. Murray, L.D. Lauer, M.I. Luster, R.W. Luebke, D.O. Adams, J.H. Dean, Correlation of murine susceptibility to tumor, parasite and bacterial challenge with altered cell-mediated immunity following systemic exposure to the tumor promoter phorbol myristate acetate. International Journal of Immunopharmacology. ,vol. 7, pp. 491- 500 ,(1985) , 10.1016/0192-0561(85)90068-2
R. Herberman, Ortaldo, Natural killer cells: their roles in defenses against disease Science. ,vol. 214, pp. 24- 30 ,(1981) , 10.1126/SCIENCE.7025208