Lead sulfide near-infrared quantum dot bioconjugates for targeted molecular imaging.
作者： Rebekah A Drezek , Nastassja Lewinski , Jiantang Sun , Kun Fu , Ming-Qiang Zhu
DOI:
关键词: Fluorescence 、 Materials science 、 Near-infrared spectroscopy 、 Molecular imaging 、 Quantum dot 、 Nanotechnology 、 Medical imaging 、 Tissue imaging 、 Lead sulfide 、 Performed Imaging
摘要: In this paper, we report the use of lead sulfide quantum dot (PbS QD) bioconjugates as near infrared (NIR) contrast agents for targeted molecular imaging with expanded emission wavelengths beyond 1000 nm. The red-shifted band, coupled small particle size, which will facilitate clearance, both afford PbS QDs unique properties noninvasive, high resolution in vivo NIR applications. We have performed experiments at level using surface-modified QDs, together our lab-built system. This novel instrumentation and fluorescent agent enabled us to study relatively unexplored biomedical spectral region 900–1200 Preliminary experimental results indicate that PbS-QD/antibody are promising candidates future tissue
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