Incidence and severity of invasive Streptococcus pneumoniae, group A Streptococcus, and group B Streptococcus infections among pregnant and postpartum women.

摘要: Background The epidemiology of streptococcal infection in pregnant and postpartum women is poorly described recent literature. We used data from multistate surveillance for invasive Streptococcus pneumoniae, group A (GAS), B (GBS) infections to estimate disease incidence severity these populations. Methods Cases were reported through the Centers Disease Control Prevention Active Bacterial Core surveillance, an active population- laboratory-based system. case was defined as illness a woman aged 15-44 years with streptococcus isolated normally sterile body site during 2007-2009. Pregnant or status recorded at time culture. Incidence calculated cases per 1000 woman-years use national Census data; 95% confidence intervals on basis λ distribution. multivariable logistic regression explore associations between hospital length stay, marker severity. Results identified 1848 women; 6.0% pregnant, 7.5% postpartum. had higher mean GBS disease, compared nonpregnant (0.04 [range, 0.03-0.05 woman-years] vs 0.02 0.02-0.02 woman-years]). Postpartum elevated all 3 pathogens, (S. pneumoniae: 0.15 0.09-0.25 0.052 0.049-0.056 woman-years]; GAS: 0.56 0.42-0.70 0.019 0.017-0.021 GBS: 0.49 0.36-0.64 0.018 0.016-0.020 Neither pregnancy nor associated longer stay among infected any pathogens. Conclusions Although do not appear be more severe women, have 20-fold increased GAS GBS, women.