Radiographic and Histopathologic Features in Sarcoidosis: A Pictorial Display

作者: Faisal Shaikh , Fereidoun G. Abtin , Ryan Lau , Rajan Saggar , John A. Belperio

DOI: 10.1055/S-0040-1712534

关键词: RadiologyLobeProgressive diseaseIn patientSarcoidosisMedicineThoracic lymph nodeVolume lossRadiographyFibrosis

摘要: Sarcoidosis is a multisystemic granulomatous disorder that can affect virtually any organ. However, pulmonary and thoracic lymph node involvement predominates; abnormalities on chest radiographs are present in 80 to 90% of patients with sarcoidosis. High-resolution computed tomographic (HRCT) scans superior X-rays assessing extent disease, some CT features may discriminate an active inflammatory component (which be amenable therapy) from fibrosis (for which therapy not indicated). Typical findings HRCT include micronodules, perilymphatic bronchocentric distribution, perihilar opacities, varying degrees fibrosis. Less common mass-like or alveolar miliary mosaic attenuation, honeycomb cysts, cavitation. With progressive fibrosis, architectural distortion, upper lobe volume loss hilar retraction, coarse linear bands, bullae observed. We discuss the salient sarcoidosis (with major focus features) classical radiographic histopathological images few extrapulmonary sites.

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