Screening for colorectal cancer in an asymptomatic average-risk population

作者: Guo-Wei Liu , Quan-Cai Cai

DOI: 10.11569/WCJD.V17.I28.2958

关键词: MedicinePast medical historyUnivariate analysisAsymptomaticPopulationColorectal cancerBody mass indexOncologyMultivariate analysisInternal medicineRed meat

摘要: AIM: To establish a risk prediction model and scoring system for adenomatous polyps. METHODS: A cross-sectional study was performed in consecutive asymptomatic averagerisk patients. The potential factors were selected from the following aspects: general data, past medical history, personal dietary frequency of defecation, menstrual history. chi-square test t-test used univariate analysis. Univariates with P value equal to or lower than 0.25 perform multivariate Potential predictive gradually using stepwise regression analysis build estimate colorectal cancer. Scores assigned each factor according β evaluate precision ability model. RESULTS: prevalences polyps, adenoma, progressive adenocarcinoma infiltrating cancer 21.5%, 7.9%, 1.2% 2.0%, respectively. identified polys included gender, education level, history smoking drinking, occupation, intake fruit, milk, pickled fried food as well red meat, body mass index (BMI), alcohol tea consumption. These polys. History smoking, fruit intake, meat three independent polyps also established: patients score more 1 considered have CONCLUSION: built this relatively high diagnostic efficiency an average-risk population. They are expected be predict among persons.

参考文章(17)
Charles S. Fuchs, Edward L. Giovannucci, Graham A. Colditz, David J. Hunter, Meir J. Stampfer, Bernard Rosner, Frank E. Speizer, Walter C. Willett, Dietary Fiber and the Risk of Colorectal Cancer and Adenoma in Women The New England Journal of Medicine. ,vol. 340, pp. 169- 176 ,(1999) , 10.1056/NEJM199901213400301
B. C. Morson, H. J. R. Bussey, Magnitude of risk for cancer in patients with colorectal adenomas British Journal of Surgery. ,vol. 72, pp. s23- s25 ,(1985) , 10.1002/BJS.1800721315
Philip Schoenfeld, Brooks Cash, Andrew Flood, Richard Dobhan, John Eastone, Walter Coyle, James W Kikendall, Hyungjin Myra Kim, David G Weiss, Theresa Emory, Arthur Schatzkin, David Lieberman, None, Colonoscopic screening of average-risk women for colorectal neoplasia. The New England Journal of Medicine. ,vol. 352, pp. 2061- 2068 ,(2005) , 10.1056/NEJMOA042990
Maite Betés, Miguel A Munoz-Navas, José M Duque, Ramón Angós, Elena Macías, Jose C Súbtil, Maite Herraiz, Susana De La Riva, Miguel Delgado-Rodríguez, Miguel A Martínez-González, Use of colonoscopy as a primary screening test for colorectal cancer in average risk people. The American Journal of Gastroenterology. ,vol. 98, pp. 2648- 2654 ,(2003) , 10.1111/J.1572-0241.2003.08771.X
Maite Betés Ibáñez, Miguel A Muñoz-Navas, José M Duque, Ramón Angós, Elena Macı́as, José Carlos Súbtil, Maite Herraiz, Susana de la Riva, Miguel Delgado-Rodrı́guez, Miguel A Martı́nez-Gonzélez, Diagnostic value of distal colonic polyps for prediction of advanced proximal neoplasia in an average-risk population undergoing screening colonoscopy. Gastrointestinal Endoscopy. ,vol. 59, pp. 634- 641 ,(2004) , 10.1016/S0016-5107(04)00155-5
L. C. Vinikoor, D. J. Robertson, J. A. Baron, W. B. Silverman, R. S. Sandler, Cholecystectomy and the risk of recurrent colorectal adenomas. Cancer Epidemiology, Biomarkers & Prevention. ,vol. 16, pp. 1523- 1525 ,(2007) , 10.1158/1055-9965.EPI-07-0243
Aesun Shin, Martha J. Shrubsole, Reid M. Ness, Huiyun Wu, Rashmi Sinha, Walter E. Smalley, Yu Shyr, Wei Zheng, Meat and meat-mutagen intake, doneness preference and the risk of colorectal polyps: The Tennessee colorectal polyp study International Journal of Cancer. ,vol. 121, pp. 136- 142 ,(2007) , 10.1002/IJC.22664
Otto S. Lin, Richard A. Kozarek, Drew B. Schembre, Kamran Ayub, Michael Gluck, Nico Cantone, Maw–Soan Soon, Jason A. Dominitz, Risk stratification for colon neoplasia: screening strategies using colonoscopy and computerized tomographic colonography. Gastroenterology. ,vol. 131, pp. 1011- 1019 ,(2006) , 10.1053/J.GASTRO.2006.08.015
Timothy M McCashland, Pat de Garmo, Randall Brand, Elizabeth Lyden, Gender differences in colorectal polyps and tumors. The American Journal of Gastroenterology. ,vol. 96, pp. 882- 886 ,(2001) , 10.1016/S0002-9270(00)02431-X
Catherine Dubé, Alaa Rostom, Gabriela Lewin, Alexander Tsertsvadze, Nicholas Barrowman, Catherine Code, Margaret Sampson, David Moher, The use of aspirin for primary prevention of colorectal cancer: a systematic review prepared for the U.S. Preventive Services Task Force. Annals of Internal Medicine. ,vol. 146, pp. 365- 375 ,(2007) , 10.7326/0003-4819-146-5-200703060-00009