Complementary vascular-protective actions of magnesium and taurine: A rationale for magnesium taurate

摘要: By a variety of mechanisms, magnesium functions both intracellularly and extracellularly to minimize the cytoplasmic free calcium level, [Ca2+]i. This may be chief reason why correction deficiency, or induction hypermagnesemia by parenteral infusion, exerts antihypertensive, anti-atherosclerotic, anti-arrhythmic antithrombotic effects. Although amino acid taurine can increase systolic transients in cardiac cells (and thus has positive inotropic activity), it other actions which tend reduce Indeed, animal clinical studies, lowers elevated blood pressure, retards cholesterol-induced atherogenesis, prevents arrhythmias stabilizes platelets--effects parallel those magnesium. The complex taurate have considerable potential as vascular-protective nutritional supplement, might also administered parenterally, an alternative sulfate, treatment acute myocardial infarction well pre-eclampsia. effects diabetes deserve particular attention, since improve insulin sensitivity, lessen risk for micro- macrovascular complications diabetes.