The Drosophila insulator proteins CTCF and CP190 link enhancer blocking to body patterning

作者: Man Mohan , Marek Bartkuhn , Martin Herold , Angela Philippen , Nina Heinl

DOI: 10.1038/SJ.EMBOJ.7601851

关键词: Insulator (genetics)EnhancerHox geneBiologyDrosophila ProteinCTCFHomeotic geneDrosophila melanogasterGeneticsBithorax complex

摘要: Insulator sequences guide the function of distantly located enhancer elements to the appropriate target genes by blocking inappropriate interactions. In Drosophila, five different …

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