Apparent diffusion coefficients in benign and secondary progressive multiple sclerosis by nuclear magnetic resonance

摘要: The diffusion characteristics of water in brain white matter were studied patients with benign and secondary progressive multiple sclerosis (MS), also normal controls. In the MS patients, both lesions normal-appearing (NAWM) examined to assess whether pathological differences might be evident from behavior. A volume-selective technique was used reduce data acquisition time improve reliability precision measurements. This allowed time-dependence apparent coefficients assessed. While patient groups showed an elevated coefficient, no between two found. addition, NAWM for compared control group, although this only statistically significant a disease course. degree elevation coefficient within individual measured not related disability patient. Pathological different courses, if they exist, have been detected study diffusion.