2-(Chlorocarbonyl)-2-mesitylketene, a new building block for the synthesis of 4-hydroxy-3-mesityl tetronic acids
作者： Folker Lieb , J Benet-Buchholz , T Fäcke , R Fischer , A Graff
DOI: 10.1016/S0040-4020(01)00293-9
关键词: Block (telecommunications) 、 Chemistry 、 Medicinal chemistry 、 Reaction conditions 、 Substitution (logic) 、 Ketone
摘要: Investigation of the reaction (chlorocarbonyl)mesitylketene with ketones led to discovery a new synthetic pathway which yields 4-hydroxy-3-mesityl tetronic acids. Depending on conditions and substitution pattern starting ketone, expected products, i.e. 4-hydroxy-3-mesitylpyrones, can nevertheless be obtained.
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