Early laparoscopic cholecystectomy is superior to delayed acute cholecystitis: a meta-analysis of case–control studies

作者: Amy M. Cao , Guy D. Eslick , Michael R. Cox

DOI: 10.1007/S00464-015-4325-4

关键词: Meta-analysisComplicationHepatologyRandomized controlled trialCase-control studyMedicineAbdominal surgeryMortality rateSurgeryBile ductInternal medicine

摘要: Since the advent of laparoscopic cholecystectomy (LC) there has been continued debate regarding management acute cholecystitis with either early or delayed LC. Nearly all studies have demonstrated that LC a significantly shorter total length hospital stay compared Although previous randomized controlled trials and meta-analysis shown clinical outcomes to favour surgery, practice continues vary worldwide. In addition, is much confusion in optimal timing for definitions varying from 72 h 7 days. There numerous case–control investigating cholecystitis. The aim this paper pool results investigate including mortality rates, complication conversion rates open procedures. A search electronic databases was performed published between 1985–February 2015. Results 77 showed statistically significant reductions mortality, complications, bile duct leaks, injuries, wound infections, blood loss associated within 72-h window optimal, patients operated after still benefit surgery surgery. duration symptoms should not influence surgeons’ willingness operate acutely. Early clearly superior most recent evidence-based strongly suggests be standard care

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