Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis
作者： G. Beaudoin , M. , Goyette , P. , Boucher
DOI: 10.1371/JOURNAL.PGEN.1003723
关键词: Ligase activity 、 Polymorphism (computer science) 、 Genotyping 、 Genome-wide association study 、 Inflammatory bowel disease 、 Biology 、 Allele 、 Genetic architecture 、 Genetic association 、 Genetics 、 Genetics(clinical) 、 Cancer research 、 Ecology, Evolution, Behavior and Systematics 、 Molecular biology
摘要: Genome-wide association studies and follow-up meta-analyses in Crohn's disease (CD) and ulcerative colitis (UC) have recently identified 163 disease-associated loci that meet …
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