A developmentally regulated activity that unwinds RNA duplexes.
作者： B BASS
DOI: 10.1016/0092-8674(87)90239-X
关键词: RNA silencing 、 RNA 、 Biology 、 Molecular biology 、 Non-coding RNA 、 Cell biology 、 Sense (molecular biology) 、 RNA-dependent RNA polymerase 、 RNA editing 、 Nuclease protection assay 、 Antisense RNA
摘要: We have attempted to use antisense RNA techniques in the developing Xenopus embryo and found that although hybrids form between sense RNAs, they are transient. Our studies indicate this is due presence of an activity unwinds RNA:RNA hybrids. The present at low, but detectable, levels oocytes, increases during oocyte maturation, exists high throughout early embryogenesis. has been characterized S100 extracts. denaturation a specific hybrid inhibited by addition second duplexed not single-stranded RNA, DNA, or double-stranded DNA.
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