Afatinib: First Global Approval

作者: Rosselle T. Dungo , Gillian M. Keating

DOI: 10.1007/S40265-013-0111-6

关键词: Cancer researchMedicineEpidermal growth factor receptorCancerAfatinibLung cancerTyrosine kinaseEuropean unionErbBPharmacologyAutophosphorylation

摘要: … Afatinib, an irreversible inhibitor of the ErbB family of tyrosine kinases, is under development with Boehringer Ingelheim for the once-daily, oral treatment of cancer. Afatinib … of afatinib, …

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