Leg Symptoms in Peripheral Arterial Disease

作者: Mary McGrae McDermott , Philip Greenland , Kiang Liu , Jack M. Guralnik , Michael H. Criqui

DOI: 10.1001/JAMA.286.13.1599

关键词: Lower limb painClaudicationDepression (differential diagnoses)AsymptomaticPhysical therapyMedicinePreferred walking speedSeverity of illnessIntermittent claudicationExertion

摘要: ContextPersons with lower-extremity peripheral arterial disease (PAD) are often asymptomatic or have leg symptoms other than intermittent claudication (IC).ObjectiveTo identify clinical characteristics and functional limitations associated with a broad range of identified among patients PAD.Design, Setting, ParticipantsCross-sectional study 460 men women PAD 130 without PAD, who were consecutively, conducted between October 1998 and January 2000 at 3 Chicago-area medical centers.Main Outcome MeasuresAnkle-brachial index score less 0.90; scores from 6-minute walk, accelerometer-measured physical activity over 7 days, repeated chair raises, standing balance (full tandem stand), 4-m walking velocity, San Diego claudication questionnaire, Geriatric Depression Score Short-Form, the Walking Impairment Questionnaire.ResultsAll groups had poorer functioning participants without PAD. The following values for without IC vs those IC. Participants in group pain on exertion rest (n = 88) higher (poorer) score neuropathy (5.6 3.5; P<.001), prevalence of diabetes mellitus (48.9% 26.7%; P<.001), and spinal stenosis (20.8% 7.2%; P .002). The atypical exertional pain/carry (exertional than IC associated through [n 41]) atypical exertional leg pain/stop that causes one to stop 90]) better group. group without pain/inactive (no in individual who walks ≤6 blocks per week 28]) and rest Adjusting age, sex, race, comorbidities compared IC, achieved greater distance walk (404.3 vs 328.5 m; P<.001) likely to stop during (6.8% 36%; .002). The slower time completing 5 raises (13.5 11.9 seconds; .009), completed stand frequently (37.5% 60.0%; .004), velocity (0.80 0.90 m/s; P<.001).ConclusionsThere is wide persons beyond that of classic Comorbid may contribute these PAD. Functional impairments found every symptom group, degree functional limitation varies depending type symptom.

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