Effect of sodium nitroprusside on myocardial performance and venous tone.
作者： Richard Gmeiner , Jörg Riedl , Holger Baumgartner
DOI: 10.1016/0014-2999(75)90051-5
关键词: Contractility 、 Preload 、 Ventricular pressure 、 Cardiac output 、 Cardiology 、 Venous tone 、 Sodium nitroprusside 、 Perfusion 、 Medicine 、 Internal medicine 、 Afterload
摘要: The action of sodium nitroprusside upon the mechanical performance isolated, working rat heart and on isolated bull veins has been studied. Cumulative concentrations 1--1000 ng per ml had no effect left ventricular pressure, end-diastolic dp/dtmax, cardiac output calculated wall stiffness hearts with constant rate, preload afterload. Isolated strips contracted noradrenaline showed a dose dependent relaxation by in 5--1000 ml. This study shows that direct myocardial contractility causes venous relaxation.
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