Prevalence of incidental actionable germline mutations in 1,000 advanced cancer patients on a prospective somatic genomic profiling program.

作者： Funda Meric-Bernstam , Lauren Brusco , Molly S Daniels , Louise C Strong , Kenna Rael Shaw

DOI: 10.1200/JCO.2015.33.15_SUPPL.1510

关键词: Bioinformatics 、 Advanced cancer 、 Precision oncology 、 Clinical significance 、 Genomic profiling 、 Germline mutation 、 DNA sequencing 、 Germline 、 Somatic cell 、 Medicine

摘要: 1510 Background: Next generation sequencing is increasingly used in cancer research and precision oncology. This practice may also reveal germline variants of potential clinical significance. We he...

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Prevalence of incidental actionable germline mutations in 1,000 advanced cancer patients on a prospective somatic genomic profiling program.

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Prevalence of incidental actionable germline mutations in 1,000 advanced cancer patients on a prospective somatic genomic profiling program.

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