The expression and clinical relevance of PD-1, PD-L1, and TP63 in patients with diffuse large B-cell lymphoma.
作者： Xia Fang , Bing Xiu , Zhizhang Yang , Weizhe Qiu , Long Zhang
DOI: 10.1097/MD.0000000000006398
关键词: Medicine 、 Cancer research 、 RNA 、 Diffuse large B-cell lymphoma 、 Cluster of differentiation 、 Tumor Protein 63 、 Chromosomal translocation 、 Regulation of gene expression 、 Lymphoma 、 PD-L1
摘要: AbstractLatest study showed that a novel translocation between programmed cell death ligand 1 (PD-L1) (cluster of differentiation 274) and TP63 (tumor protein 63) can be found in diffuse large B-cell lymphoma (DLBCL), resulting their conjunct overexpression tumor cells at RNA level. However, t
sci-hub.se 参考文章(38)
Sumanta K Pal, Robert A Figlin, Mark Chang, Adriana Hu, Programmed death-1 inhibition in renal cell carcinoma: clinical insights and future directions. Clinical advances in hematology & oncology. ,vol. 12, pp. 90- ,(2014)
Junichi Kiyasu, Hiroaki Miyoshi, Akie Hirata, Fumiko Arakawa, Ayako Ichikawa, Daisuke Niino, Yasuo Sugita, Yuji Yufu, Ilseung Choi, Yasunobu Abe, Naokuni Uike, Koji Nagafuji, Takashi Okamura, Koichi Akashi, Ryoichi Takayanagi, Motoaki Shiratsuchi, Koichi Ohshima, Expression of programmed cell death ligand 1 is associated with poor overall survival in patients with diffuse large B-cell lymphoma. Blood. ,vol. 126, pp. 2193- 2201 ,(2015) , 10.1182/BLOOD-2015-02-629600
Cliff Tabin, Arlene Sharpe, Daniel Caput, Christopher Crum, Frank McKeon, Annie Yang, Ronen Schweitzer, Deqin Sun, Mourad Kaghad, Nancy Walker, Roderick T. Bronson, p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development Nature. ,vol. 398, pp. 714- 718 ,(1999) , 10.1038/19539
Alea A. Mills, Binhai Zheng, Xiao-Jing Wang, Hannes Vogel, Dennis R. Roop, Allan Bradley, p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature. ,vol. 398, pp. 708- 713 ,(1999) , 10.1038/19531
James Krempski, Lavakumar Karyampudi, Marshall D. Behrens, Courtney L. Erskine, Lynn Hartmann, Haidong Dong, Ellen L. Goode, Kimberly R. Kalli, Keith L. Knutson, Tumor-Infiltrating Programmed Death Receptor-1 + Dendritic Cells Mediate Immune Suppression in Ovarian Cancer Journal of Immunology. ,vol. 186, pp. 6905- 6913 ,(2011) , 10.4049/JIMMUNOL.1100274
Matthew J. Ahearne, Kaljit Bhuller, Roger Hew, Hazem Ibrahim, Kikkeri Naresh, Simon D. Wagner, Expression of PD-1 (CD279) and FoxP3 in diffuse large B-cell lymphoma Virchows Archiv. ,vol. 465, pp. 351- 358 ,(2014) , 10.1007/S00428-014-1615-5
Kathleen M. Mahoney, Gordon J. Freeman, David F. McDermott, The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma Clinical Therapeutics. ,vol. 37, pp. 764- 782 ,(2015) , 10.1016/J.CLINTHERA.2015.02.018
David M. Dorfman, Julia A. Brown, Aliakbar Shahsafaei, Gordon J. Freeman, Programmed death-1 (PD-1) is a marker of germinal center-associated T cells and angioimmunoblastic T-cell lymphoma The American Journal of Surgical Pathology. ,vol. 30, pp. 802- 810 ,(2006) , 10.1097/01.PAS.0000209855.28282.CE
Noriyasu Fukushima, Toshimi Satoh, Naoko Sueoka, Akemi Sato, Masaru Ide, Takashi Hisatomi, Nobuo Kuwahara, Rika Tomimasu, Naoko Tsuneyoshi, Noriko Funai, Masayuki Sano, Osamu Tokunaga, Eisaburo Sueoka, Clinico-pathological characteristics of p63 expression in B-cell lymphoma Cancer Science. ,vol. 97, pp. 1050- 1055 ,(2006) , 10.1111/J.1349-7006.2006.00284.X
Maren Cam, Hemant K. Bid, Linlin Xiao, Gerard P. Zambetti, Peter J. Houghton, Hakan Cam, p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damage. Journal of Biological Chemistry. ,vol. 289, pp. 4083- 4094 ,(2014) , 10.1074/JBC.M113.530303