Anticentromere antibody in primary biliary cirrhosis.
作者： RM Bernstein , ME Callender , JM Neuberger , GR Hughes , ROGER Williams
DOI: 10.1136/ARD.41.6.612
关键词: Primary biliary cirrhosis 、 Medicine 、 Hepatitis 、 Pathology 、 Context (language use) 、 Autoantibody 、 Telangiectasia 、 Antibody 、 Calcinosis 、 Scleroderma
摘要: An autoantibody specific for the centromere region of chromosomes and recently detected in serum patients with scleroderma was found ther 10 (9.1%) 110 consecutive presenting primary biliary cirrhosis. It exclusively among those scleroderma, giving a prevalence 50% that group, all telangiectasia or calcinosis had antibody. not 80 chronic active hepatitis, including 'autoimmune' variety. The pathogenetic significance anticentromere antibody is yet established, but this study confirms its specificity context
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