Lack of P-Glycoprotein Expression by Low-Dose Fractionated Radiation Results from Loss of Nuclear Factor-κB and NF-Y Activation in Oral Carcinoma Cells

作者: Mohammed Momin Shareef , Brandee Brown , Shahin Shajahan , Sabapathi Sathishkumar , Susanne M. Arnold

DOI: 10.1158/1541-7786.MCR-07-0221

关键词: Cell cultureTUNEL assayTranscription factorSmall interfering RNAGene silencingBiologyCancer researchApoptosisMolecular biologyProgrammed cell deathP-glycoprotein

摘要: … study, two squamous cell carcinoma oral cavity cell lines, T-… clinical dose of 2 Gy or low-dose fractionated radiation … , heterogeneous make-up, many tumors tend to be resistant to …

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