Targeting of oxidative stress and inflammation through ROS/NF-kappaB pathway in phosphine-induced hepatotoxicity mitigation

作者: Hamed Haghi Aminjan , Seyed Reza Abtahi , Ebrahim Hazrati , Mohsen Chamanara , Maryam Jalili

DOI: 10.1016/J.LFS.2019.116607

关键词: Oxidative stressGlutathioneApoptosisPharmacologyNecrosisSOD1CatalaseChemistryResveratrolInflammationGeneral Pharmacology, Toxicology and PharmaceuticsGeneral Biochemistry, Genetics and Molecular BiologyGeneral Medicine

摘要: … The results indicated that phosphine causes an alteration in oxidative stress markers including elevation of ROS, and GSH level, MPO activity, reduction in SOD, catalase and G6PD …

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